1930
- On October 24th, Clarence H. Mackay dedicated Mackay Science Hall and presented it to the University.
- Theodore H. Miller, the first African-American graduate of the University, completed a Bachelor of Science in Electrical Engineering.
1936
- Clarence H. Mackay purchased and donated nearly 27 acres of adjacent land, increasing the campus footprint by nearly 50%.
- University enrollment surpassed 1000 students for the first time.
1938
- The Northwest Association of Secondary and Higher Schools accredited the University.
- Max C. Fleischmann initiated the then-largest giving program in University history, including scholarships for Native-American students.
- President Clark resigned on September 30th.
1939
- The administration of President Leon W. Hartman began with a formal inauguration on December 15th after serving as interim president for more than a year. He was the University’s 6th president.
- Campus held the first Winter Carnival.
1941
- The state legislature authorized a bond issue to construct a new gymnasium.
- Commencement ceremonies included celebrations for the 50th anniversary of the graduation of the University's first four-year class.
1942
- After no major capital improvements for 30 years, the University constructed a new engineering facility, later named the Stanley Palmer Engineering Building.
- The University’s war effort included the development of additional special summer session offerings.
1943
- The Army and Army Air Force training contingents arrived at the University.
- President Hartman died in office on August 27th.
1944
- The University celebrated the inauguration of John O. Moseley as its 7th president on October 12th.
1946
- The University canceled a football game at Mississippi State when its state athletic director requested that Nevada play without African-American players.
1948
- The Twentieth Century Fox filmed Apartment for Peggy on campus, one of several movies shot on University grounds during the 1940s.
1949
- Gilbert E. Parker became acting president on July 1st after the resignation of John Mosely.
1951
- On June 10th and 11th, the University celebrated the inauguration of Malcolm A. Love as its 8th president.
- One full-time and two-part University instructors began offering classes in Las Vegas. A total of 38 students enrolled.
1952
- Stella Mason Parson became the first African American woman graduate, with a Bachelor of Arts in English.
1953
- On June 8th, the University celebrated the inauguration of Minard W. Stout as the 9th president.
1954
- The University established a Nevada Southern branch in Las Vegas with 269 students.
1956
- The legislature funded a new building to support business education. The building was named for Silas E. Ross, a former regent who served for 25 years.
1957
- The first Las Vegas campus building opened.
- Students began taking classes in the Orvis School of Nursing, which received funding from Arthur E. and Mae Zenke Orvis.
1958
- Construction concluded on Jot Travis Student Union, which alumni helped to fund.
1959
- The University established the Desert Research Institute.
- On April 19th, the University celebrated the inauguration of Charles J. Armstrong as the 10th president.